2014年

Category-1: Hematopoiesisand Immune Environment
2-H-W32-5-0/P : YANAGIHARA Toyoshi (Kyushu University)
Identification of a novel molecule essential for Aire expression and self-tolerance

Category-2: B cells
2-G-W29-8-O/P : YAMAZAKI Nao (National Center for Global health and Medicine)
IgM+ plasma cells contribute to the sufficient production of IgG by secreting IL-10 and IL-13

Category-3: T cells
2-D-W23-6-O/P : KAMIMURA Daisuke (Hokkaido University)
Characterization of T-Red mutant mouse line having reduced naive T cells

Category-4: Helper T cells
3-E-W44-5-O/P : SANO Teruyuki (New York University)
Cytokine requirement for Th17 cell differentiation in response to Segmented filamentous bacteria colonization

Category-5: Regulatory T cells
3-D-W42-16-O/P : MURAKAMI Ryuichi (RIKEN)
Foxp3 and BATF cooperatively controls regulatory T cell homeostasis in non-lymphoid tissues

Category-6: Innate lymphocytes
1-B-W2-8-O/P : MIYAJIMA Michio (RIKEN)
Type III innate lymphoid cells enhance antibody production by splenic marginal zone B cells

Category-7: Dendritic cells and macrophages
2-C-W22-1-O/P : NIIZUMA Kouta (University of Tsukuba)
Identification and characterization of human CD300H, the eighth member of the CD300-family receptors

Category-8: Antigen presentation
2-E-W26-9-O/P : KISHIDA Kazuki (Osaka University)
Processing of cellular misfolded protein complexed with MHC class II molecules

Category-9: Trafficking
1-F-W9-13-O/P : HARADA Yosuke (Kyushu University)
The role of DOCK8 in migration and activation of effector CD4+ T cells during immune responses

Category-10: Mast cells & Granulocytes
2-J-W36-7-O/P : ANDO Tomoaki (RIKEN)
Mast cells and the Stat5 activation pathway are required for allergen-induced and spontaneous skin inflammation

Category-11: Allergy
1-J-W18-3-O/P : TSAI Shin han (Osaka University)
E-NPP3 (CD203c) negatively regulates ATP-dependent allergic responses by basophils and mast cells

Category-12: Cytokines and chemokines
3-G-W47-17-O/P : OGURA Hideki (Hokkaido University)
ZFZ (zinc finger motif containing protein Z) promotes the inflammation amplifier by regulating NF-κB DNA binding activity

Category-13: Immunological memory
1-G-W11-1-O/P : KONDO Taisuke (Keio University)
Generation of mouse CD4⁺ stem cell memory T cells by Wnt signaling and by Notch signaling

Category-14: Virus infection
2-I-W34-2-O/P : SUGIMOTO Naoshi (Kyoto University)
Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system

Category-15: Mycofungal / parasite infection
3-I-W52-4-O/P : UENO Keigo (National Institute of Infectious Diseases)
Efficacy of dendritic cell-mediated immunization for the pulmonary infection with highly virulent fungus Cryptococcus gattii

Category-16: Bacterial infection
3-I-W51-9-O/P : TSUCHIYA Kohsuke (Kyoto University)
NLRP3 and ASC contribute to host defense against pneumococcal pneumonia in an inflammasome-independent manner

Category-17: Endogeneous innate immunity and inflammation
2-E-W25-6-O/P : IMAMURA Tomoko (Kyoto University)
N4bp1-mediated nascent RNA decay controls cytokine mRNA expression

Category-18: Mucosal-Skin Immunity
3-H-W49-5-O/P : GOTO Yoshiyuki (Columbia University)
Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation

Category-19: Tolerance and Immune suppression
1-H-W13-3-O/P : LIN Youwei (NCNP)
Inverse vaccination for autoimmune diseases by sensitization of superior dominant peptide through efficient induction of functionally stable regulatory T cells possessing high antigen-specificity

Category-20: Organ-specific autoimmune diseases
1-F-W10-2-O/P : ASASHIMA Hiromitsu (University of Tsukuba)
The suppressive ability of altered peptide ligands to M3R reactive T cells in M3R induced autoimmune sialadenitis

Category-21: Rheumatoid arthritis
2-F-W28-1-O/P : KONDO Yuya (University of Tsukuba)
RORγt+Foxp3+ regulatory T cells regulates the development of autoimmune arthritis in mice

Category-22: Systemic autoimmune diseases
3-F-W45-7-O/P : MORITA Kaoru (The University of Tokyo)
The role of Egr2 and Egr3 in regulating immune homeostasis

Category-23: Tumor immunity
2-B-W19-8-O/P : MAEDA Takuya (Kyoto University)
Regeneration of EB virus LMP2 specific CTLs utilizing iPS technology

Category-24: Human Immunology (immunointervention)
3-C-W40-7-O/P : NAKACHI Shinichiro (The University of Tokyo)
A quantitative alteration of human CD4+CD25-LAG3+Tregs in patients with rheumatoid arthritis

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